Semaphorin-3A is a repulsive but attractive renal guidance cue to therapy
نویسندگان
چکیده
منابع مشابه
Repulsive guidance cue semaphorin 3A in urine predicts the progression of acute kidney injury in adult patients from a mixed intensive care unit.
BACKGROUNDS Predicting the development of acute kidney injury (AKI) in the critical care setting is challenging. Although several biomarkers showed somewhat satisfactory performance for detecting established AKI even in a heterogeneous disease-oriented population, identification of new biomarkers that predict the development of AKI accurately is urgently required. METHODS A single-center pros...
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Semaphorin 3A (Sema3A) is a secreted disulfide-bound homodimeric molecule that induces growth cone collapse and repulsion of axon growth in the nervous system. Recently, it has been demonstrated that Sema3A is produced by endothelial cells and inhibits integrin function in an autocrine fashion. In this study, we investigated the effects of Sema3A on platelet function by using 2 distinct human S...
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ژورنال
عنوان ژورنال: Journal of Molecular Medicine
سال: 2014
ISSN: 0946-2716,1432-1440
DOI: 10.1007/s00109-014-1210-x